BioReact Pre-Seed Announcement

FOR IMMEDIATE RELEASE

BioReact Raises $1.07M Oversubscribed Pre-Seed to Power the AI and Analytics Layer for Bioprocess Development

Indianapolis, IN — BioReact, the AI and analytics platform powering modern bioprocess development and optimization, today announced it has raised a $1.07 million oversubscribed pre-seed round, led by New Stack Ventures, with participation from PhyCap, Hurricane Ventures, Plug and Play, Soren White, and Service Provider Capital.

BioReact provides a unified data and intelligence layer for teams running bioprocesses, bringing together online, offline, and metadata into a structured, time-aligned foundation. On top of this foundation, BioReact applies advanced analytics and machine learning to help scientists understand performance drivers, compare experiments across scales, and optimize outcomes such as yield, titer, and robustness without requiring coding or data science expertise.

The new capital will be used to accelerate go-to-market efforts and expand BioReact’s product capabilities, with a focus on:

  • Scale-up intelligence, enabling teams to translate bench and pilot data into more predictable manufacturing outcomes

  • Strain engineering insights, linking genetic and experimental data to bioprocess performance

  • Downstream processing analytics, extending optimization beyond upstream operations to recovery and purification workflows

“Bioprocess data is fragmented, underutilized, and increasingly complex as teams scale,” said Mitchell Castetter, Founder and CEO of BioReact. “BioReact is becoming the system of record and intelligence layer for bioprocess development, helping teams move faster, reduce failed runs, and make better decisions earlier. This round allows us to bring that capability to more organizations while expanding the platform across the full bioprocess lifecycle.”

New Stack Ventures cited BioReact’s vertical focus and data advantage as key drivers of the investment. “We’re impressed by how BioReact is tackling one of the biggest bottlenecks in bioprocessing: turning fragmented experimental data into something teams can actually learn from. By building a centralized system of record that reflects how scientists run experiments, BioReact is becoming core infrastructure for bioprocess development” said a Ariella Frank from New Stack Ventures.

BioReact is currently used by teams across biopharma, industrial biotech, and synthetic biology, supporting organisms ranging from bacteria and fungi to mammalian systems. As biomanufacturing continues to grow in complexity and scale, BioReact aims to serve as the backbone for data-driven bioprocess development.

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